Myelofibrosis is a rare type of bone marrow cancer that is related to a group of blood cancers called myeloproliferative tumors. Simple blood tests and bone marrow biopsy can diagnose myelofibrosis. Myelofibrosis is also referred to as chronic bone marrow sclerosis, unknowable myelodysplasia, leukemia megakaryocyte myeloproliferation, idiopathic myelofibrosis, and leukocytosis. According to a report published by the American Leukemia and Lymphoma Society (LLS), about 1.5 out of every 100,000 people in the United States develop myelofibrosis each year. Patients over 50 years of age are more susceptible to this disease, but it can occur at any age. Myelofibrosis affects women and men with the same frequency, but in children, it affects girls more than boys. Although the treatment options available for myelofibrosis are few and almost all suggestive, the FDA-approved (JAK inhibitor) drug Ruxotinib forms the main line of defense against myelofibrosis.
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Currently, there are many research projects under review that focus on the development of specific treatments for myelofibrosis. CTI BioPharma is studying the use of oral pacomitinib in the treatment of myelofibrosis, Gilead Sciences is developing a molecule-CYT387 for the treatment of primary myelofibrosis, and Incyte is studying the effect of ruxolitinib on myelofibrosis patients. Alternative drug delivery strategy. In addition, the innovator of ruxolitinib, Novartis, continues to try to propose new drug usages in all stages of myelofibrosis.
The market is divided into blood transfusion, chemotherapy, androgen therapy and stem cell/bone marrow transplantation according to the type of treatment. According to end users, the market is further divided into hospitals, clinics and bone marrow transplant centers. The market is also segmented according to the types of drugs available for treatment options, such as hydroxyurea, immunomodulators, JAK inhibitors (ruxotinib), etc.
In the report, the Transparency Market Report (TMR) analyzed in detail the driving factors and limitations of the global myelofibrosis market. It also provides insight into market segments and regions.
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The global myelofibrosis market: drivers and constraints
The incidence of myelofibrosis in developing economies is relatively high, which has increased the demand for various treatment options for myelofibrosis. Due to heavy investment in research and development, appropriate reimbursement conditions, and a large number of patients with myelofibrosis, the market growth is expected to rise further. In addition, this increase can also be attributed to other factors, such as lifestyle upgrades, increased numbers of smokers, and increased incidence of genetic diseases. On the contrary, limited understanding and high cost of treatment may limit the growth of the global myelofibrosis market.
Due to the easy availability of chemotherapy drugs, the chemotherapy part is expected to make a significant contribution to the revenue generated by the market. The U.S. Food and Drug Administration approved Ruxotinib, the only chemotherapeutic drug specifically used to treat myelofibrosis, which will promote the global myelofibrosis treatment market during the aforementioned period.
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Global Myelofibrosis Market: Regional Outlook
Based on geographic location, the global bone marrow fibrosis market is divided into Europe, Asia Pacific, North America and other regions of the world. According to the report, in terms of value, it is well known that North America has the largest market share. The growth in the region can be attributed to increased awareness, high prevalence of diseases, higher percentages of health care expenditures compared to other economies, and appropriate reimbursement. Due to its large elderly population, increased disposable income and improved healthcare facilities, the Asia-Pacific region is expected to occupy a large share of the market.
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The main players operating in the global myelofibrosis market are Novartis, Roche, Merck, Eli Lilly, Celgene, Amgen, Bristol-Myers Squibb, Insett and Gilead Sciences.
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